Acute renal failure is a common complication in patients with spontaneous bacterial peritonitis (SBP) and is associated with a high risk of mortality.
This module discusses the uses of albumin in treating patients with SBP.
Key Takeaways
Acute renal failure is a common complication in patients with SBP and is associated with a high risk of mortality
Systemic inflammation caused by SBP is responsible for a severe splanchnic vasodilation and a reduction in cardiac contractility causing a reduction in effective circulating volume and renal hypoperfusion
The administration of albumin at the dose of 1.5 gr/kg of body weight on day 1 and 1 gr/kg of body weight on day 3 reduces the incidence of ARF and improves survival in patients with SBP
Human albumin exerts an anti-inflammatory effects on the heart of patients with cirrhosis and improves cardiac contractility
