Pathophysiology of decompensated cirrhosis

This module describes the mechanisms driving decompensated cirrhosis and acute on chronic liver failure.

Module material
Overview
Key Takeaways

Module overview

This module describes the mechanisms driving decompensated cirrhosis and acute on chronic liver failure.

Key Takeaways

Portal hypertension, pathological bacterial translocation, systemic inflammation, circulatory dysfunction and metabolic alterations are the main driver of decompensation of cirrhosis and acute on chronic liver failure
Targeting those pathophysiological mechanisms can change the natural history of decompensated cirrhosis

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